It is produced by the pituitary gland and converted by the liver into a protein called somatomedin-C or IGF-1 (insulin-like growth factor 1). It is IGF-1 that is partially responsible for the growth hormone functions in the body.
Growth hormone contributes to ongoing tissue repair, cell rejuvenation, bone strength, brain function, enzyme production, and the integrity of hair, nails and skin. The signs of growth hormone deficiency are significantly correlated to the signs of aging: body composition shifts from lean muscle mass and high energy levels to increased fat/body weight and low energy levels, decreased bone mineralization (bone growth slows), vitality ebbs, and cardiovascular disease and mortality increase.
Concurrent with physiological effects, decreased human growth hormone also has psychosocial effects that include impaired physical performance, poor sleep, and decreased social interaction.
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