Melatonin, as most know, is the hormone most associated with sleep and the circadian rhythm. This hormone has displayed various positive benefits on the immune system as well.
As melatonin levels have been found to be low in those women suffering from endometrial cancer, its supplementation was investigated in this application.
Hormone Replacement Therapy
When used together with estrogen therapy in animal models of menopause, melatonin supplementation demonstrated that the hormone significantly decreased endometrial cell proliferation and lower body weight in test animals. This study suggests that melatonin may be a useful compound as a cancer preventative.
Study Effect of Melatonin on Intra-abdominal Fat in Correlation with Endometrial Proliferation in Ovariectomized Rats found “The addition of melatonin to estrogen replacement treatment is associated with a decrease in endometrial proliferation and prevents the appearance of cellular atypia. The presented results suggest that melatonin supplementation may play an important role in the prophylaxis of endometrial cancer in menopause.”
Learn more about how to use Hormone Replacement Therapy for Weight Loss.
